Interstate 27 (I-27) is an intrastate Interstate Highway, entirely in the U.S. state of Texas, running north from U.S. Route 84 and U.S. Route 87 in Lubbock to Interstate 40, U.S. Route 60, U.S. Route 87 and U.S. Route 287 in Amarillo. These two cities are the only control cities on I-27; other cities and towns served by I-27 include (from south to north) New Deal, Abernathy, Hale Center, Plainview, Kress, Tulia, Happytown, and Canyon. In Amarillo, I-27 is commonly known as the Canyon Expressway (or Canyon E-Way), although it is also called Canyon Drive on its access roads. I-27 was officially designated the Marshall Formby Memorial Highway after former attorney and Texas State Senator Marshall Formby in 2005. The entire length of I-27 replaced part of U.S. Route 87 for through traffic.
In the Intertropolis & Routeville series and comics, as mentioned in the episode "Amarillo and Lubbock", the southern terminus of I-27 is at Interstate 20 in Big Spring.