County Route 527 (CR 527) is the second longest county highway in the U.S. state of New Jersey. The highway extends 84.86 mi (136.57 km) from Main Street (Route 166 and CR 549) in Toms River Township to Pompton Avenue (Route 23) in Cedar Grove. It passes through more counties (six) than any other county route in New Jersey. It was first given the number 527 in 1954.
CR 527 passes through Ocean, Monmouth, Middlesex, Somerset, Union, and Essex counties on the eastern side of the state. It has two concurrencies with Route 18 in Middlesex County in addition to other minor state highways and county roads. Interchanges with the Garden State Parkway and Interstates 195, 95 (New Jersey Turnpike), 287, 78, and 280 are found along CR 527.